Ecological and evolutionary implications of immunological priming in invertebrates.

نویسندگان

  • Tom J Little
  • Alex R Kraaijeveld
چکیده

Invertebrates have an immune response that differs considerably from the acquired immune response found in vertebrates. However, new studies indicate that past experience with a pathogen can provide individual invertebrates, or their descendants, with enhanced immunity. This prophylactic effect, termed immunological priming, is functionally similar to the acquired immune response in vertebrates. This newfound complexity of invertebrate immunity begs investigation into the conditions under which immunological priming should evolve, and its consequences for population dynamics.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Insect Immunity Shows Specificity in Protection upon Secondary Pathogen Exposure

Immunological memory in vertebrates, conferring lasting specific protection after an initial pathogen exposure, has implications for a broad spectrum of evolutionary, epidemiological, and medical phenomena . However, the existence of specificity in protection upon secondary pathogen exposure in invertebrates remains controversial . To separate this functional phenomenon from a particular mechan...

متن کامل

Senescence in immune priming and attractiveness in a beetle.

Age-related decline in immune activity is referred to as immunosenescence and has been observed for both the adaptive immune response of vertebrates and the innate immune system of invertebrates. Because maintaining a basic level of immune defence and mounting an immune response is costly, optimal investment in immune function should vary over a wide range of individual states such as the indiv...

متن کامل

Multigenerational immune priming in an invertebrate parthenogenetic Artemia to a pathogenic Vibrio campbellii.

Invertebrates were traditionally thought to rely on the innate arm of the defense system to fight against pathogens [1,2], and adaptivity or memory of immune responses were previously considered the hallmark of a highly evolved immune system, only present in vertebrates [3]. However, there are now evidences indicating that invertebrates have immunological specificity and memory of a kind that i...

متن کامل

The evolutionary dynamics of within-generation immune priming in invertebrate hosts.

While invertebrates lack the machinery necessary for 'acquired immunity', there is increasing empirical evidence that exposure to low levels of disease may 'prime' an invertebrate's immune response, increasing its defence to subsequent exposure. Despite this increasing empirical data, there has been little theoretical attention paid to immune priming. Here, we investigate the evolution of immun...

متن کامل

Within and transgenerational immune priming in an insect to a DNA virus.

Invertebrates mount a sophisticated immune response with the potential to exhibit a form of immune memory through 'priming'. Increased immune protection following early exposure to bacteria has been found both later in life (within generation priming) and in the next generation (transgeneration priming) in a number of invertebrates. However, it is unclear how general immune priming is and wheth...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Trends in ecology & evolution

دوره 19 2  شماره 

صفحات  -

تاریخ انتشار 2004